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Interpreted as:

title:(IRF8-dependent AND DCs AND play AND a AND key AND role AND in AND the AND regulation AND of AND CD8 AND T AND cell AND responses AND to AND epithelial-derived AND antigen AND in AND the AND steady AND state AND but AND not AND in AND inflammation)

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1 Conference paper

IRF8-dependent DCs play a key role in the regulation of CD8 T cell responses to epithelial-derived antigen in the steady state but not in inflammation

. This demonstrates that IRF8-DCs are crucial for the rapid tolerization of CD8 T cells reactive towards epithelial-derived antigen in steady state, but are not essential for the induction of CTLs in an inflammatory setting such as found in infection.

Year: 2016

Language: English

jpeb id cnhamlf kog
2 Conference paper

IRF8-dependent DCs play a key role in the regulation of CD8 T cell responses to epithelialderived antigen in the steady state but not in inflammation

ccre.Irf8fl/fl and control chimeras. Taken together, this demonstrates that IRF8-DCs are crucial for therapid tolerization of CD8 T cells reactive towards epithelial-derived antigen in steady state, but are notessential for the induction of CTLs in an inflammatory setting such as found in infection.

Year: 2016

Language: English

fncj kheimlbdoa gp

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